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Low Carb
Low Calorie
vs. Low Carbohydrate
by Tanya Zilberter, PhD
It was clearly demonstrated in small size mammals such as mice and rats.
How exactly calorie restriction works to prolong life is unknown. One of working
hypotheses is that dietary restriction alters some, maybe many, of the nervous
and hormonal functions that regulate the body fuel use. 
Low Calorie and Low Carb
This article continues the topic: Calorie
Restriction and Life Span
One of working hypotheses is that dietary restriction alters some, maybe
many, of the nervous and hormonal functions that regulate the body fuel
use. Dr. Masoro's findings on carbohydrate metabolism are in accordance
with this view.
"Diet-restricted rats can use carbohydrate fuel as effectively as "ad
libitum" fed rats, while maintaining lower plasma glucose and insulin level.
Maintenance of these low levels may protect against [any] long-term damaging
actions of these substances. Dietary restriction also protects against oxidative
damage and, of course, oxidative damage is probably an inevitable component
of fuel use." (Journals of Gerontology, Series A, Biological Sciences &
Medical Sciences. 50(3):B148-54, May 1995)
However, the dietary source of carbohydrate has not been widely investigated
in this respect. Researchers in Department of Nutrition, University of California,
Davis, hypothesized that the dietary carbohydrate source may affect the
life span of rats independent of caloric restriction, and found that incorporating
refined sugars into 60 percent of a calorie-restrictive diet (instead of
complex carbohydrates) removed all beneficial effects!
"Our data support the hypothesis that the dietary source of carbohydrate,
i.e., sucrose versus cornstarch, can significantly affect [the] life span
independently of caloric intake." (Journals of Gerontology, Series A, Biological
Sciences & Medical Sciences. 50A(1):B48-53, 1995)
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